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1

Differential targeting and processing of procathepsin D in normal and transformed murine 3T3 fibroblasts

Ciro Isidoro, Marina Démoz, Daniela De Stefanis, Francesco M. Baccino, Andrej Hasilik, Gabriella Bonelli

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 154 KB

english, 1997

2

Mis-sorting of procathepsin D in metastogenic tumor cells is not due to impaired synthesis of the phosphomannosyl signal

Ciro Isidoro, Francesco M. Baccino, Andrej Hasilik

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 211 KB

english, 1997

3

Lysosomal segregation of a mannose-rich glycoprotein imparted by the prosequence of myeloperoxidase

Ulrike Bening, Roberta Castino, Norbert Harth, Ciro Isidoro, Andrej Hasilik

Journal:

Journal of Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 154 KB

english, 1998

4

The Potential of P1 Site Alterations in Peptidomimetic Protease Inhibitors as Suggested by Virtual Screening and Explored by the Use of CC-Coupling Reagents

Steffen Weik, Torsten Luksch, Andreas Evers, Jark Böttcher, Christoph A. Sotriffer, Andrej Hasilik, Hans-Gerhard Löffler, Gerhard Klebe, Jörg Rademann

Journal:

Year:

2006

Language:

english

File:

PDF, 479 KB

english, 2006

5

The catalytically inactive precursor of cathepsin D induces apoptosis in human fibroblasts and HeLa cells

Olga Schestkowa, Dominik Geisel, Ralf Jacob, Andrej Hasilik

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 234 KB

english, 2007

6

Sequential detection of antigens in Western blots with differently colored products

Nicole Theisen, Eckhard Schulze Lohoff, Kurt von Figura, Andrej Hasilik

Journal:

Analytical Biochemistry

Year:

1986

Language:

english

File:

PDF, 794 KB

english, 1986

7

Immunoprecipitation of labeled antigens with eupergit C1Z

Susanne Grässel, Angelika Rölling, Andrej Hasilik

Journal:

Analytical Biochemistry

Year:

1989

Language:

english

File:

PDF, 790 KB

english, 1989

8

Porins facilitate nitric oxide-mediated killing of mycobacteria

Daniela Leite Fabrino, Christopher K.E. Bleck, Elsa Anes, Andrej Hasilik, Rossana C.N. Melo, Michael Niederweis, Gareth Griffiths, Maximiliano Gabriel Gutierrez

Journal:

Microbes and Infection

Year:

2009

Language:

english

File:

PDF, 1.05 MB

english, 2009

9

A protocol for combined delipidation and subfractionation of membrane proteins using organic solvents

Bernd Schröder, Andrej Hasilik

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 190 KB

english, 2006

10

PMN responses in chronic periodontal disease: evaluation by gingival crevicular fluid enzymes and elastase-alpha-1-proteinase inhibitor complex

Rainer Buchmann, Andrej Hasilik, Martha E. Nunn, Thomas E. Van Dyke, Dieter E. Lange

Journal:

Journal of Clinical Periodontology

Year:

2002

Language:

english

File:

PDF, 168 KB

english, 2002

11

The proteome of lysosomes

Bernd A. Schröder, Christian Wrocklage, Andrej Hasilik, Paul Saftig

Journal:

Year:

2010

Language:

english

File:

PDF, 389 KB

english, 2010

12

Human and hamster procathepsin D, although equally tagged with mannose-6-phosphate, are differentially targeted to lysosomes in transfected BHK cells

C. Isidoro, Francesco M. Baccino, Andrej Hasilik

Journal:

Cell and Tissue Research

Year:

1998

Language:

english

File:

PDF, 114 KB

english, 1998

13

Integral and Associated Lysosomal Membrane Proteins

Bernd Schröder, Christian Wrocklage, Cuiping Pan, Ralf Jäger, Bernd Kösters, Helmut Schäfer, Hans-Peter Elsässer, Matthias Mann, Andrej Hasilik

Journal:

Year:

2007

Language:

english

File:

PDF, 1.47 MB

english, 2007

14

Increased elongation of N-acetyllactosamine repeats in doubly glycosylated lysozyme with a particular spacing of the glycosylation sites

Ralph Melcher, Hans-Wilhelm Grosch, Oliver Grosse, Andrej Hasilik

Journal:

Glycoconjugate Journal

Year:

1998

Language:

english

File:

PDF, 113 KB

english, 1998

15

IL-10 Synergizes with IL-4 and IL-13 in Inhibiting Lysosomal Enzyme Secretion by Human Monocytes and Lamina Propria Mononuclear Cells from Patients with Inflammatory Bowel Disease

Norbert Lugering, Torsten Kucharzik, Henning Stein, Gunther Winde, Andreas Lugering, Andrej Hasilik, Wolfram Domschke, Reinhard Stoll

Journal:

Digestive Diseases and Sciences

Year:

1998

Language:

english

File:

PDF, 375 KB

english, 1998

16

Carbohydrate mediated recognition of lysosomal enzymes by cell surface receptors

Kurt Von Figura, Abdul Waheed, Andrej Hasilik

Journal:

Journal of Biosciences

Year:

1983

Language:

english

File:

PDF, 133 KB

english, 1983

17

Neutrophil elastase is associated with serglycin on its way to lysosomes in U937 cells

Peter Lemansky, Eva Smolenova, Christian Wrocklage, Andrej Hasilik

Journal:

Cellular Immunology

Year:

2007

Language:

english

File:

PDF, 661 KB

english, 2007

18

Plasmid vectors with a 5′-hybrid intron facilitate high-level glycoprotein expression in CHO-cells

Ralph Melcher, Hans-Wilhelm Grosch, Andrej Hasilik

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2002

Language:

english

File:

PDF, 169 KB

english, 2002

19

Abnormal lysosomal sorting with an enhanced secretion of cathepsin D precursor molecules bearing monoester phosphate groups

Johannes Faulhaber, Anthony Fensom, Andrej Hasilik

Journal:

European Journal of Cell Biology

Year:

1998

Language:

english

File:

PDF, 1.70 MB

english, 1998

20

Effects of Antibiotics on the Development and Stability of Mitochondrial Enzymes in Saccharomyces cerevisiae

Coen P. M. Görts, Andrej Hasilík

Journal:

Year:

1972

Language:

english

File:

PDF, 579 KB

english, 1972

21

Compartmentation of the Tryptophan-Synthase-Proteolyzing System in Saccharomyces cerevisiae

Andrej HASILIK, Hannelore MÜLLER, Helmut HOLZER

Journal:

Year:

1974

Language:

english

File:

PDF, 639 KB

english, 1974

22

Biosynthesis of the Vacuolar Yeast Glycoprotein Carboxypeptidase Y : Conversion of Precursor into the Enzyme

Andrej HASILIK, Widmar TANNER

Journal:

Year:

1978

Language:

english

File:

PDF, 899 KB

english, 1978

23

Carbohydrate Moiety of Carboxypeptidase Y and Perturbation of Its Biosynthesis

Andrej HASILIK, Widmar TANNER

Journal:

Year:

1978

Language:

english

File:

PDF, 1.02 MB

english, 1978

24

Oligosaccharides in Lysosomal Enzymes : Distribution of High-Mannose and Complex Oligosaccharides in Cathepsin D and β-Hexosarninidase

Andrej HASILIK, Kurt VON FIGURA

Journal:

Year:

1981

Language:

english

File:

PDF, 584 KB

english, 1981

25

Impaired Phosphorylation of Lysosomal Enzymes in Fibroblasts of Patients with Mucolipidosis III

Andrej HASILIK, Abdul WAHBED, Michael CANTZ, Kurt von FIGURA

Journal:

Year:

1982

Language:

english

File:

PDF, 505 KB

english, 1982

26

Lysosomal Enzyme Precursors in Human Fibroblasts : Activation of Cathepsin D Precursor in vitro and Activity of β-Hexosaminidase A Precursor towards Ganglioside GM2

Andrej HASILIK, Kurt von FIGURA, Ernst CONZELMANN, Heidi NEHRKORN, Konrad SANDHOFF

Journal:

Year:

1982

Language:

english

File:

PDF, 533 KB

english, 1982

27

Enhanced Breakdown of Arylsulfatase A in Multiple Sulfatase Deficiency

Abdul WAHEED, Andrej HASILIK, Kurt VON FIGURA

Journal:

Year:

1982

Language:

english

File:

PDF, 526 KB

english, 1982

28

Synthesis and stability of arylsulfatase A and B in fibroblasts from multiple sulfatase deficiency

Friedhelm STECKEL, Andrej HASILIK, Kurt VON FIGURA

Journal:

Year:

1985

Language:

english

File:

PDF, 1.02 MB

english, 1985

29

Multiple sulfatase deficiency: Degradation of arylsulfatase A and B after endocytosis in fibroblasts

Friedhelm STECKEL, Andrej HASILIK, Kurt VON FIGURA

Journal:

Year:

1985

Language:

english

File:

PDF, 1.42 MB

english, 1985

30

Steroid sulfatase : Biosynthesis and processing in normal and mutant fibroblasts

Jon CONARY, Anette NAUERTH, Gary BURNS, Andrej HASILIK, Kurt von FIGURA

Journal:

Year:

1986

Language:

english

File:

PDF, 949 KB

english, 1986

31

Association of the precursor of cathepsin D with coated membranes : Kinetics and carbohydrate processing

Thorsten MARQUARDT, Thomas BRAULKE, Andrej HASILIK, Kurt VON FIGURA

Journal:

Year:

1987

Language:

english

File:

PDF, 952 KB

english, 1987

32

Suppression of the ‘uncovering’ of mannose-6-phosphate residues in lysosomal enzymes in the presence of NH4Cl

Ciro ISIDORO, Jürgen RADONS, Franceso M. BACCINO, Andrej HASILIK

Journal:

Year:

1990

Language:

english

File:

PDF, 839 KB

english, 1990

33

Elongation of N-Acetyllactosamine Repeats in Diantennary Oligosaccharides

Mathias Hummel, Hans C. Hedrich, Andrej Hasilik

Journal:

Year:

1997

Language:

english

File:

PDF, 793 KB

english, 1997

34

Enhanced degradation of cathepsin D synthesized in the presence of the threonine analog β-hydroxynorvaline

Mathias Hentze, Andrej Hasilik, Kurt Von Figura

Journal:

Archives of Biochemistry and Biophysics

Year:

1984

Language:

english

File:

PDF, 1.91 MB

english, 1984

35

Deficiency of UDP-N-acetylglucosamine: Lysosomal enzyme N-acetylglucosamine-1-phosphotransferase in organs of I-cell patients

Abdul Waheed, Regina Pohlmann, Andrej Hasilik, Kurt von Figura, August van Elsen, Jules G. Leroy

Journal:

Biochemical and Biophysical Research Communications

Year:

1982

Language:

english

File:

PDF, 1.11 MB

english, 1982

36

Sulfated oligosaccharides in human lysosomal enzymes

Thomas Braulke, Annette Hille, Wieland B. Huttner, Andrej Hasilik, Kurt von Figura

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 836 KB

english, 1987

37

Mannose 6-phosphate/insulin-like growth factor II receptor: Distinct binding sites for mannose 6-phosphate and insulin-like growth factor II

Thomas Braulke, Christa Causin, Abdul Waheed, Ulrich Junghans, Andrej Hasilik, Peter Maly, RenéE. Humbel, Kurt von Figura

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 396 KB

english, 1988

38

Conditions for a reliable application of the lysoplate method in the determination of lysozyme

Dwijendra K. Gupta, Kurt von Figura, Andrej Hasilik

Journal:

Clinica Chimica Acta

Year:

1987

Language:

english

File:

PDF, 754 KB

english, 1987

39

Biosynthesis of acid α-glucosidase in late-onset forms of glycogenosis type II (Pompe's disease)

Friedhelm Steckel, Volkmar Gieselmann, Abdul Waheed, Andrej Hasilik, Kurt von Figura, Ronald Oude Elferink, Roelof Kalsbeek, Joseph M. Tager

Journal:

Year:

1982

Language:

english

File:

PDF, 1.20 MB

english, 1982

40

Selective inactivity of TGF-β/decorin complexes

Heinz Hausser, Arndt Gröning, Andrej Hasilik, Elke Schönherr, Hans Kresse

Journal:

Year:

1994

Language:

english

File:

PDF, 243 KB

english, 1994

41

Glycohydrolases β-hexosaminidase and β-galactosidase are associated with lipid microdomains of Jurkat T-lymphocytes

Alessandro Magini, Alice Polchi, Brunella Tancini, Lorena Urbanelli, Andrej Hasilik, Carla Emiliani

Journal:

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

42

Identification of plasma membrane associated mature β-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts

Simona Mencarelli, Cristina Cavalieri, Alessandro Magini, Brunella Tancini, Luisa Basso, Peter Lemansky, Andrej Hasilik, Yu-Teh Li, Vanna Chigorno, Aldo Orlacchio, Carla Emiliani, Sandro Sonnino

Journal:

Year:

2005

Language:

english

File:

PDF, 201 KB

english, 2005

43

Cathepsin D expression is decreased in Alzheimer's disease fibroblasts

Lorena Urbanelli, Carla Emiliani, Carlo Massini, Emanuele Persichetti, Antonio Orlacchio, Giuliana Pelicci, Sandro Sorbi, Andrej Hasilik, Giorgio Bernardi, Aldo Orlacchio

Journal:

Neurobiology of Aging

Year:

2008

Language:

english

File:

PDF, 807 KB

english, 2008

44

High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells

Marina Démoz, Roberta Castino, Carlo Follo, Andrej Hasilik, Bonnie F. Sloane, Ciro Isidoro

Journal:

Protein Expression and Purification

Year:

2006

Language:

english

File:

PDF, 538 KB

english, 2006

45

Membrane-active antimicrobial peptides and human placental lysosomal extracts are highly active against mycobacteria

Prajna Jena, Bibhuti Mishra, Matthias Leippe, Andrej Hasilik, Gareth Griffiths, Avinash Sonawane

Journal:

Year:

2011

Language:

english

File:

PDF, 387 KB

english, 2011

46

Presence of detergent-resistant microdomains in lysosomal membranes

Antje Taute, Kristin Wätzig, Brigitte Simons, Christiane Lohaus, Helmut E Meyer, Andrej Hasilik

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 185 KB

english, 2002

47

Human cathepsin D precursor is associated with a 60 kDa glycosylated polypeptide

Susanne Grässel, Andrej Hasilik

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 976 KB

english, 1992

48

Genetic heterogeneity of steroid sulfatase deficiency revealed with cDNA for human steroid sulfatase

Jon T. Conary, Gerhard Lorkowski, Bernhard Schmidt, Regina Pohlmann, Gerhard Nagel, Helmut E. Meyer, Christiane Krentler, Jan Cully, Andrej Hasilik, Kurt von Figura

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 879 KB

english, 1987

49

Application of magnetic chromatography to the isolation of lysosomes from fibroblasts of patients with lysosomal storage disorders

Ole Diettrich, Kevin Mills, Andrew W Johnson, Andrej Hasilik, Bryan G Winchester

Journal:

Year:

1998

Language:

english

File:

PDF, 164 KB

english, 1998

50

Enzymatic phosphorylation of lysosomal enzymes in the presence of UDP-N-acetylglucosamine. Absence of the activity in l-cell fibroblasts

Andrej Hasilik, Abdul Waheed, Kurt von Figura

Journal:

Biochemical and Biophysical Research Communications

Year:

1981

Language:

english

File:

PDF, 595 KB

english, 1981